Most Popular Cities to Visit in South America

Buenos Aires, Argentina

Big, sprawling Buenos Aires, the capital of Argentina, is cosmopolitan and yet retains a neighborhood feel in the barrios. Sightseeing, nightlife, including the sensual tango, is a must in this sophisticated city.

For culture seekers, Buenos Aires is one of the most popular South American cities to visit.

Rio de Janeiro, Brazil

Truly a cidade maravilhosa, Rio is spectacularly located, and to live up to the scenery, cariocas and visitors enjoy a vivid lifestyle nestled between fabulous beaches and rainforested hills.

Rio de Janeiro is known for its nightlife, offering opportunities to party until the sun rises. Taking your vacation around Carnival means experiencing a celebration like no other.

Santiago, Chile

Chile’s capital city is cosmopolitan, serving as the financial, cultural, and political center of the country. It’s graced with tree-lined streets, parks, distinctive neighborhoods, and a plethora of restaurants and hotels.

Moreover, Santiago is close to ski resorts and coastal beaches, making it an ideal base for excursions throughout the Central Valley.

Sao Paulo, Brazil

As South America’s largest city and Brazil’s center of trade and industry, the hardworking residents of Sao Paulo know how to enjoy leisure time, balancing work and play. Despite not being considered one of the most attractive South American cities, it offers numerous activities to engage its visitors.

Bogota, Colombia

Nestled high in the Andes at an elevation of 2620 m (8646 ft), Santa Fé de Bogotá showcases a city of contrasts, where contemporary high-rises coexist with colonial churches. This vibrant city is replete with universities, theaters, and exceptional galleries and museums.

Consequently, it’s a great city to arrive in before exploring other parts of Colombia. Discount flights abound, allowing easy access to Cartagena, the coffee triangle, and the picturesque city of Popayan.

Lima, Peru

Lima, known as the City of Kings since its founding, holds significant historical value. While it faces many typical urban challenges found in modern South American cities, those who simply pass through to reach other attractions miss out on rich history and culture.

Do not overlook vibrant neighborhoods like Barranco or local markets to savor freshly prepared ceviche from street vendors.

Caracas, Venezuela

Caracas serves as Venezuela’s capital and largest city, acting as the hub of commerce, culture, and economics. Additionally, it serves as a base for exploring the country’s stunning attractions, including Angel Falls and the vast Llanos.

Cartagena, Colombia

The historic walled city of Cartagena represents a stronghold against pirates and invaders in its early days. Today, it welcomes visitors with its colonial charm, vibrant nightlife, and proximity to enticing attractions.

Often hailed as the jewel of South America, Cartagena is among the most beautiful South American cities, making it a perfect stop before venturing to The Lost City or Taganga, as well as Playa Blanca, which is one of Colombia’s most stunning beaches.

Quito, Ecuador

As Ecuador’s capital, Quito combines colonial history with modernity, captivating visitors with its charm. The city serves as an excellent starting point to explore the scenic Pan-American Highway, both north and south.

Nevertheless, as in many South American countries, it is advisable to be vigilant against pickpockets and petty theft. Always safeguard your belongings, especially in crowded areas.

Salvador, Brazil

This lively city is characterized by Candomble culture, vibrant beaches, unique architecture, and an array of lively street activities.

Final Thoughts

This is merely a glimpse into the wealth of South American cities awaiting exploration. Whether seeking cultural enrichment or beach relaxation, each region offers unique experiences tailored for the adventurous traveler.